{"product_id":"blockbuster-drugs-9780199737680","title":"BLOCKBUSTER DRUGS","description":"\u003cdiv class=\"book-description\"\u003e\n\u003cp\u003e\u003cstrong\u003eBLOCKBUSTER DRUGS\u003c\/strong\u003e by LI. hardcover edition. ISBN: 9780199737680.\u003c\/p\u003e\n\u003cp\u003eFor the worlds largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizers Lipitor, GlaxoSmithKlines Advair, AstraZenecas Seroquel, and Sanofi-Aventis and Bristol-Myers Squibbs Plavix all came off patent in the crucial U.S. market. This so-called \"patent cliff\" meant hundreds of billions of dollars in lost revenue and has pharmaceutical developers scrambling to create new drugs and litigating to extend current patent protections.\n\nHaving spent most of his career in drug discovery in \"big pharma,\" Dr. Li now delivers an insiders account of how the drug industry ascended to its plateau and explores the nature of the turmoil it faces in the coming years. He begins with a survey of the landscape before \"blockbuster drugs,\" and proceeds to describe how those drugs were discovered and subsequently became integral to the business models of large pharmaceutical companies. For example, in early 1980s, Tagamet, the first \"blockbuster drug,\" transformed a minor Philadelphia-based drug maker named SmithKline \u0026amp; French into the worlds ninth-largest pharmaceutical company in terms of sales. The project that delivered Tagamet was nearly terminated several times because research efforts begun in 1964 produced no apparent results within the first eleven years. Similar stories accompany the discovery and development of now-ubiquitous prescription drugs, among them Claritin, Prilosec, Nexium, Plavix, and Ambien.\n\nThese stories, and the facets of the pharmaceutical industry that they reveal, can teach us valuable lessons and reveal many crucial aspects about the future landscape of drug discovery. As always, Dr. Li writes in a readable style and intersperses fascinating stories of scientific discovery with engaging human drama.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Oxford University Press, USA","offers":[{"title":"Default Title","offer_id":44984544329781,"sku":"ByrdShop_0199737681","price":44.36,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8139\/0901\/files\/9780199737680_c5c0d3d8-57fa-45d6-a53d-274844fb4457.jpg?v=1778684741","url":"https:\/\/atxbooks.com\/products\/blockbuster-drugs-9780199737680","provider":"ATX Books","version":"1.0","type":"link"}