{"product_id":"the-first-miracle-drugs-how-the-sulfa-drugs-transformed-medicine","title":"The First Miracle Drugs: How the Sulfa Drugs Transformed Medicine","description":"\u003cp\u003eIn the decade from 1935-1945  while the Second World War raged in Europe  a new class of medicines capable of controlling bacterial infections launched a therapeutic revolution that continues today. The new medicines were not penicillin and antibiotics  but sulfonamides  or sulfa drugs. The sulfa drugs preceded penicillin by almost a decade  and during World War II they carried the main therapeutic burden in both military and civilian medicine. Their success stimulated a rapid expansion of research and production in the international pharmaceutical industry  raised expectations of medicine  and accelerated the appearance of new and powerful medicines based on research. The latter development created new regulatory dilemmas and unanticipated therapeutic problems. The sulfa drugs also proved extraordinarily fruitful as starting points for new drugs or classes of drugs  both for bacterial infections and for a number of important non-infectious diseases. This book examines this breakthrough in medicine  pharmacy  and science in three parts. Part I shows that an industrial research setting was crucial to the success of the revolution in therapeutics that emerged from medicinal chemistry. Part II shows how national differences shaped the reception of the sulfa drugs in Germany  France  Britain  and the United States. The author uses press coverage of the day to explore popular perceptions of the dramatic changes taking place in medicine. Part III documents the impact of the sulfa drugs on the American effort in World War II. It also shows how researchers came to an understanding of how the sulfa drugs worked  adding a new theoretical dimension to the science of pharmacology and at the same time providing a basis for the discovery of new medicinal drugs in the 1940s  1950s  and 1960s. A concluding chapter summarizes the transforming impact of the sulfa drugs on twentieth-century medicine  tracing the therapeutic revolution from the initial breakthrough in the 1930s to the current search for effective treatments for AIDS and the new horizons opened up by the human genome project and stem cell research.\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44985225576501,"sku":"ByrdShop_019518775X","price":97.35,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8139\/0901\/files\/9780195187755.jpg?v=1770852920","url":"https:\/\/atxbooks.com\/products\/the-first-miracle-drugs-how-the-sulfa-drugs-transformed-medicine","provider":"ATX Books","version":"1.0","type":"link"}